soluble guanyl cyclase (guanylate cyclase-1)

Function

• activated by nitric oxide in the presence of Mg+2 or Mn+2
• half maximally inhibited at Ca+2 of 120 nM

Cofactor: binds 1 or 2 heme groups per heterodimer

Subunits

• guanyl cyclase-alpha
• guanyl cyclase-beta

More general terms

• guanyl cyclase or guanylate cyclase
• Ca+2 binding protein
• multisubunit protein