phosphorylase-M (myophosphorylase, muscle glycogen phosphorylase, PYGM)

Function

• glycogen phosphorylase

Cofactor: pyridoxal phosphate

Structure

• homodimer
• dimers associate into a tetramer
• belongs to the glycogen phosphorylase family

Pathology

• defects in PYGM are the cause of glycogen storage disease type 5

Laboratory

• PYGM gene mutation

More general terms

• glycogen phosphorylase

Database

• UniProt: http://www.uniprot.org/uniprot/P11217.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5837
• OMIM: https://mirror.omim.org/entry/232600
• OMIM: https://mirror.omim.org/entry/608455