phosphorylase-B (brain glycogen phosphorylase, PYGB)

Function

• glycogen phosphorylase
• phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A

(1,4-alpha-D-glucosyl)(n) + phosphate
                   <-->
(1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate

Cofactor: pyridoxal phosphate

Structure

• homodimer
• dimers associate into a tetramer to form the enzymatically active phosphorylase A
• belongs to the glycogen phosphorylase family

More general terms

• glycogen phosphorylase

Database

• UniProt: http://www.uniprot.org/uniprot/P11216.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5834
• OMIM: https://mirror.omim.org/entry/138550