phosphatidylinositol-4-phosphate 5-kinase type-2 gamma; PI(4)P 5-kinase type 2 gamma; PIP5K2-gamma (PIP5K2C, PIP4K2C)

Function

• role in production of phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (ER) (putative)

phosphorylated

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
                   <-->
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate

Structure

contains 1 PI5K domain

Compartment

• cytoplasm, membrane
• mostly found in cytosol & surrounding plasma membrane
• presence in ER seems to be a prerequisite for PIP2 synthesis

More general terms

• phosphoinositide-5-kinase
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8TBX8.html