Leishmanolysin-like peptidase (invadolysin, LMLN)

Function

• essential for the coordination of mitotic progression
• plays a role in cell migration (putative)

Cofactor: binds 1 Zn+ per subunit (putative)

Structure

belongs to the peptidase M8 family

Compartment

• cytoplasm
• found in ring-likestructures resembling invadopodia
• in migrating cells it relocalizes from internal structures to the leading edge of cells

Alternative splicing

named isoforms=2

More general terms

• glycoprotein
• peptidase; peptide hydrolase

Database

• UniProt: http://www.uniprot.org/uniprot/Q96KR4.html