ichthyin (ICHN, NIPAL4)

Function

• receptor for ligands (trioxilins A3 & B3) from the hepoxilin pathway (putative)

Structure

belongs to the NIPA family

Compartment

membrane

Expression

• highly expressed in brain, lung, stomach, skin & leukocytes, & in all other tissues tested except liver, thyroid & fetal brain

Pathology

• defects in ICHN are the cause of an autosomal recessive congenital ichthyosis

More general terms

• receptor
• transmembrane 9 protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q0D2K0.html