transcription elongation factor SPT6; hSPT6; Tat-cotransactivator 2 protein; Tat-CT2 protein (SUPT6H, KIAA0162, SPT6H)

Function

• stimulates transcriptional elongation by RNA polymerase 2
• interacts with RNA polymerase 2 & the DSIF complex

Structure

• belongs to the SPT6 family
• contains 1 S1 motif domain
• contains 1 SH2 domain

Compartment

nucleus (probable)

Alternative splicing

named isoforms=3

Expression

ubiquitously expressed

More general terms

• transcription elongation factor
• phosphoprotein

Additional terms

• DRB sensitivity-inducing factor complex (DSIF complex, DSIF)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6830
• OMIM: https://mirror.omim.org/entry/601333
• UniProt: http://www.uniprot.org/uniprot/Q7KZ85.html