phosphatidylinositol N-acetylglucosaminyltransferase subunit Y (phosphatidylinositol-glycan biosynthesis class Y protein, PIG-Y, PIGY)

Function

• component of the GPI-GlcNAc transferase (GPI-GnT)
• may act by regulating the catalytic subunit PIGA
• glycolipid biosynthesis, GPI-anchor biosynthesis
• interacts directly with PIGA
• does not interact with Ras proteins

Compartment

endoplasmic reticulum membrane

Genetics

• PREY is derived from the same bicistronic transcript that encodes PIGY

More general terms

• enzyme regulatory subunit
• transmembrane 2 protein

Component of

• UDP-N-acetylglucosamine phosphatidylinositol transferase (GPI-GlcNAc transferase, GPI-GnT)

Database

• UniProt: http://www.uniprot.org/uniprot/Q3MUY2.html