tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15, HsSen15, TSEN15, SEN15)

Function

• non-catalytic subunit of the tRNA-splicing endonuclease
• although only weakly related to the S.cerevisiae SEN15 protein, it probably displays the same function within the tRNA splicing endonuclease complex

Structure

belongs to the SEN15 family

Compartment

• nucleus, nucleolus (probable)
• may be transiently localized in the nucleolus

Expression

• widely expressed
• highly expressed in testis & uterus

More general terms

• enzyme regulatory subunit

Component of

• tRNA-splicing endonuclease complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1164
• OMIM: https://mirror.omim.org/entry/608756
• UniProt: http://www.uniprot.org/uniprot/Q8WW01.html