metal transporter CNNM4 (Cyclin-M4, Ancient conserved domain-containing protein 4, CNNM4, ACDP4, KIAA1592)

Function

• probable metal transporter
• interaction with the metal ion chaperone COX11 suggests a role in sensory neuron functions (putative)
• interacts with COX11

Structure

• belongs to the ACDP family
• contains 1 CBS domain
• shares weak sequence similarity with the cyclin family, explaining its name; however it has no cyclin-like function in vivo

Compartment

cell membrane

Expression

• widely expressed
• highly expressed in heart

Notes

Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo

More general terms

• glycoprotein
• membrane protein
• carrier protein (transporter)

Database

• OMIM: https://mirror.omim.org/entry/607805
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26504
• UniProt: http://www.uniprot.org/uniprot/Q6P4Q7.html