ammonium transporter Rh type C (Rh family type C glycoprotein, Rhesus blood group family type C glycoprotein, Rh type C glycoprotein, tumor-related protein DRC2, Rh glycoprotein kidney, RHCG, C15orf6, CDRC2, PDRC2, RHGK)

Function

• electroneutral & bidirectional ammonium transporter
• may regulate transepithelial ammonia secretion

Structure

• N-glycosylated
• belongs to the ammonium transporter (TC 2.A.49) family, Rh subfamily

Compartment

• apical cell membrane
• detected at the basolateral membrane & in subapical vesicles

Expression

• expressed in brain, testis, placenta, pancreas, esophagus, prostate
• expressed in squamous epithelial tissues
• specifically expressed in kidney
• specifically expressed in fetal kidney

More general terms

• carrier protein (transporter)
• glycoprotein
• membrane protein

Database

• OMIM: https://mirror.omim.org/entry/605381
• UniProt: http://www.uniprot.org/uniprot/Q9UBD6.html