protein OSCP1 (organic solute transport protein 1, hOSCP1, oxidored-nitro domain-containing protein 1, OSCP1, C1orf102, NOR1)

Function

• role in xenobiotic clearance in placenta

Kinetic parameters:

• KM=35.0 uM for p-aminohippurate
• KM=62.3 uM for tetraethylammonium

Compartment

• basal cell membrane

Alternative splicing

named isoforms=2

Expression

• expressed predominantly in testis
• expressed in syncytiotrophoblast in placenta
• expressed in thymus & small intestine

Pathology

• abundantly expressed in tumor-derived cell lines
• role in nasopharyngeal carcinoma

More general terms

• carrier protein (transporter)

Database

• OMIM: https://mirror.omim.org/entry/608854
• UniProt: http://www.uniprot.org/uniprot/Q8WVF1.html