antigen peptide transporter (Transporter Associated with Antigen Processing, TAP)

Introduction

A pump which delivers peptides to class I MHC molecules within the endoplasmic reticulum of antigen presenting cells.

More general terms

• adenosine triphosphatase (ATPase)
• carrier protein (transporter)
• plasma membrane protein

More specific terms

• antigen peptide transporter-2 (APT2), peptide transporter TAP2, peptide transporter PSF2, peptide supply factor 2 (PSF-2), RING11, Y1, PSF2, MTP-2 or HAM-2
• Transporter Associated with Antigen Processing; antigen peptide transporter-1; peptide transporter TAP1, peptide transporter PSF1, peptide supply factor 1; PSF-1 (TAP1, APT1, RING4, Y3, MTP-1, HAM-1)