NAD isocitrate dehydrogenase

Function

• activated by increasing ADP/ATP ratios & by Ca+2 (putative)

isocitrate + NAD+ <--> 2-oxoglutarate + CO2 + NADH

Structure

• heterooligomer of subunits IDH3A (alpha), IDH3B (beta), & IDH3G (gamma) in the apparent ratio of 2:1:1

More general terms

• isocitrate dehydrogenase
• citric acid cycle enzyme
• multisubunit protein

Database

• OMIM: https://mirror.omim.org/entry/147650