neuron-restrictive silencer element (NRSE)

Introduction

NRSE is a binding site for neuron-restrictive silencer factor (NRSF). NRSF represses gene transcription in non neuronal cells through binding to NRSE. NRSF is expressed in non neuronal tissues & in undifferentiated neuronal progenitors, but not in differentiated neurons.

More general terms

• silencer element