mitochondrial carnitine/acylcarnitine carrier protein; carnitine/acylcarnitine translocase; CAC; solute carrier family 25 member 20 (SLC25A20, CAC, CACT)

Function

• mediates transport of acylcarnitines of different length across the mitochondrial inner membrane from cytosol to mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway

Structure

• belongs to the mitochondrial carrier family
• contains 3 solcar repeats

Compartment

• mitochondrial inner membrane

Pathology

• defects in SLC25A20 are the cause of carnitine-acylcarnitine translocase deficiency

More general terms

• transmembrane 6 protein
• symporter
• glycoprotein
• solute carrier family 20 (SLC20, SLC20A)
• mitochondrial protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:788
• OMIM: https://mirror.omim.org/entry/212138
• UniProt: http://www.uniprot.org/uniprot/O43772.html