CD207 (langerin, Langerhans cell specific C-type lectin, CLEC4K)
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Introduction
Type II C-type lectin.
Function
- endocytic receptor
- mannose-binding specificity
- induces the formation of Birbeck granules
- regulates membrane superimposition & zippering
Compartment
found in Birbeck granules
Expression
- exclusively expressed by Langerhans cells
More general terms
Component of
References
- ↑ Valladeau J et al Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 12:71-81, 2000 PMID: https://www.ncbi.nlm.nih.gov/pubmed/10661407
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=50489
- ↑ UniProt http://www.uniprot.org/uniprot/Q9UJ71.html