serpin B4; squamous cell carcinoma antigen 2; SCCA-2; leupin (SERPINB4, SCCA2)

Function

• may act as a protease inhibitor to modulate the host immune response against tumor cells

Structure

belongs to the serpin family, Ov-serpin subfamily

Compartment

• cytoplasm
• seems to also be secreted in plasma by cancerous cells but at a low level

Expression

squamous cells

More general terms

• serine protease inhibitor; serpin
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6318
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6318
• OMIM: https://mirror.omim.org/entry/600518
• UniProt: http://www.uniprot.org/uniprot/P48594.html