drosophila discs large [dlg] protein
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Introduction
Mutations in dlg (discs large gene) lead to a loss of tight (septate) junctions between epithelial cells & aberrant proliferation of cells in the imaginal disk. Human homolog is SAP97.
More general terms
- guanylate kinase
- cytoskeletal protein
- anti-oncoprotein (tumor suppressor protein)
- invertebrate-specific protein
Additional terms
References
- ↑ Pawson T Protein modules and signalling networks Nature 373:573 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7531822