hydroxyacid oxidase 1; glycolate oxidase 1 (HAOX1, GOX)

Function

• 2-hydroxyacid oxidase activity
• most active on the 2-carbon substrate glycolate
• glycolate pathway, 2nd step
• also active on 2-hydroxy fatty acids.

(S)-2-hydroxy acid + O2  <--> 2-oxo acid +  H2O2

Cofactor: FMN

Compartment

peroxisome

Expression

expressed in liver

More general terms

• flavoprotein
• oxidoreductase

Additional terms

• glycolate

Database

• OMIM: https://mirror.omim.org/entry/605023
• UniProt: http://www.uniprot.org/uniprot/Q9UJM8.html