nitrilase homolog 2 (NIT2)
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Function
- overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle
Structure
- belongs to the UPF0012 family
- contains 1 CN hydrolase domain
Compartment
Expression
- detected in fetal brain (at protein level)
- ubiquitous
- detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine & colon Mass spectroscopy: mass=30585; Method=maldi[2]
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9NQR4.html
- ↑ 2.0 2.1 Lin CH, Chung MY, Chen WB, Chien CH. Growth inhibitory effect of the human NIT2 gene and its allelic imbalance in cancers. FEBS J. 2007 Jun;274(11):2946-56. Epub 2007 May 4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17488281