Centrosome & spindle pole-associated protein 1 (CSPP1, CSSP)
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Function
- may play a role in cell-cycle-dependent microtubule organization
- phosphoryated
- phosphorylation increases in colcemide-treated cells
Compartment
- centrosome
- associated with mitotic spindles
Alternative splicing
named isoforms=2
Expression
- detected in testis
- expression of isoform 1 increases throughout the cell cycle & peaks in G2/M phase
- expression of isoform 2 is highest in G1 phase & decreases thereafter