restin; CAP-Gly domain-containing linker protein 1; cytoplasmic linker protein 170 alpha-2; CLIP-170; Reed-sternberg intermediate filament-associated protein; cytoplasmic linker protein 1 (CLIP1, CYLN1, RSN)

Function

• seems to be a intermediate filament associated protein that links endocytic vesicles to microtubules

Structure

contains 2 CAP-Gly domains

Compartment

• cytoplasm, cytoskeleton
• associated with the cytoskeleton

Alternative splicing

named isoforms=2; long, short

Expression

• highly expressed in the Reed-sternberg cells of Hodgkin's disease

More general terms

• cytoskeletal protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P30622.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6249
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6249
• OMIM: https://mirror.omim.org/entry/179838