protein boule-like (BOLL)

Function

• RNA-binding protein
• role in spermatogenesis
• binds to the 3'UTR of mRNAs & regulates their translation
• interacts with DAZ1 & DAZ

Structure

• belongs to the RNP DAZ family
• contains 1 DAZ-like domain contains 1 RRM domain (RNA recognition motif)

Compartment

cytoplasm

Alternative splicing

named isoforms=2

Expression

• testis specific
• not expressed in early embryos, primoridal germ cells & spermatogonial cells
• first expressed in the cytoplasm of spermatocytes, then persists through meiosis

More general terms

• RNA-binding protein

Database

• OMIM: https://mirror.omim.org/entry/606165
• UniProt: http://www.uniprot.org/uniprot/Q8N9W6.html