poly(rC)-binding protein 2 (alpha-CP2, hnRNP-E2, PCBP2)

Function

• major cellular poly(rC)-binding protein
• also binds poly(rU)
• phosphorylation diminishes poly(rC)-binding activity

Structure

• contains 3 KH domains

Compartment

• nucleus, cytoplasm
• loosely bound in nucleus
• may shuttle between nucleus & cytoplasm

Expression

ubiquitously expressed

More general terms

• RNA-binding protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/601210
• UniProt: http://www.uniprot.org/uniprot/Q15366.html