U3 small nucleolar ribonucleoprotein protein IMP3 homolog; U3 snoRNP protein IMP3; BRMS2 (IMP3, C15orf12, MRPS4)

Function

• component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). required for the early cleavages during pre-18S ribosomal RNA processing
• component of a heterotrimeric complex containing IMP3, IMP4 & MPHOSPH10
• interacts with MPHOSPH10

Structure

• belongs to the ribosomal protein S4P family
• contains 1 S4 RNA-binding domain

Compartment

nucleus, nucleolus

More general terms

• nuclear protein
• RNA-binding protein

Component of

• U3-snRNP; U3 small nuclear ribonucleoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55272
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55272
• OMIM: https://mirror.omim.org/entry/612980
• UniProt: http://www.uniprot.org/uniprot/Q9NV31.html