immunoglobulin superfamily member 11 (brain & testis-specific immunoglobulin superfamily protein, Bt-IGSF, V-set & immunoglobulin domain-containing protein 3, IGSF11, BTIGSF, CXADRL1, VSIG3)

Function

• cell adhesion molecule through homophilic interaction
• stimulates cell growth

Structure

• N-glycosylated (putative)
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 Ig-like V-type domain (immunoglobulin-like)
• the last 20 cytoplasmic amino-acids are not required for cell adhesion

Compartment

cell membrane

Alternative splicing

named isoforms=3

Expression

• abundantly expressed in testis & ovary
• expressed to a lower extent in brain, kidney & skeletal muscle

More general terms

• glycoprotein
• membrane protein
• immunoglobulin superfamily protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1524
• OMIM: https://mirror.omim.org/entry/608351
• UniProt: http://www.uniprot.org/uniprot/Q5DX21.html