ferric-chelate reductase 1 (stromal cell-derived receptor 2, SDR-2, FRRS1, SDFR2, SDR2)

Function

• ferric-chelate reductases reduce Fe+3 to Fe+2 before its transport from the endosome to the cytoplasm (putative)

Cofactor: binds 2 heme groups non-covalently (putative)

Structure

• belongs to the FRRS1 family
• contains 1 cytochrome b561 domain
• contains 1 DOMON domain
• contains 1 reelin domain

Compartment

membrane (putative)

Alternative splicing

named isoforms=2

More general terms

• glycoprotein
• oxidoreductase
• membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3910
• UniProt: http://www.uniprot.org/uniprot/Q6ZNA5.html