UNC5C-like protein (protein unc-5 homolog C-like, ZU5 & death domain-containing protein, UNC5CL, ZUD)

Function

• inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets
• interacts with p65/RELA & NFKB1

Structure

• belongs to the unc-5 family
• contains 1 death domain
• contains 1 ZU5 domain

Compartment

membrane (putative), cytoplasm

Expression

expressed in pancreas, liver & kidney

More general terms

• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IV45.html