solute carrier family 12 member 8 (cation-chloride cotransporter 9, SLC12A8, CCC9)

Function

• cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation

Structure

belongs to the SLC12A transporter family

Compartment

membrane (putative)

Alternative splicing

named isoforms=5

Expression

ubiquitous with very low level in normal skin

Pathology

• defects in SLC12A8 may be a cause of susceptibility to psoriasis vulgaris

More general terms

• glycoprotein
• membrane protein
• solute carrier family 12 (SLC12, SLC12A)

Database

• OMIM: https://mirror.omim.org/entry/604316
• UniProt: http://www.uniprot.org/uniprot/A0AV02.html