stromal interaction molecule 2 (STIM2, KIAA1482)

Function

• inhibits STIM1-mediated Ca+2 influx
• oligomer with STIM1
• phosphorylated predominantly on Ser residues

Structure

• glycosylated
• contains 1 EF-hand domain
• contains 1 SAM domain (sterile alpha motif)

Compartment

endoplasmic reticulum membrane

Expression

• expressed in all tissues & tumor cell lines examined

More general terms

• Ca+2 binding protein
• glycoprotein
• phosphoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9P246.html