protein transport protein Sec23A (SEC23-related protein A, SEC23A)

Function

• component of the COPII coat
• interacts with SEC23IP

Structure

• belongs to the SEC23/SEC24 family, SEC23 subfamily

Compartment

• smooth endoplasmic reticulum membrane
• peripheral membrane
• in the ribosome-free transitional face of the ER & associated vesicles

Pathology

• defects in SEC23A are the cause of craniolenticulosutural dysplasia

More general terms

• membrane protein
• protein subunit

Component of

• COPII coat

Database

• OMIM: https://mirror.omim.org/entry/607812
• UniProt: http://www.uniprot.org/uniprot/Q15436.html