sarcolemmal membrane-associated protein (sarcolemmal-associated protein, SLMAP, KIAA1601, SLAP, UNQ1847/PRO3577)

Function

• role in myoblast fusion
• interacts with myosin

Structure

• homodimer
• belongs to the SLMAP family
• contains 1 FHA domain

Compartment

• cell membrane, sarcolemma
• distributed in the transverse tubules & near the junctional sarcoplasmic reticulum
• detected along the Z-lines & M-lines in cardiomyocytes
• localizes to the centrosomes (microtubule-dependent)

Alternative splicing

named isoforms=8

More general terms

• membrane protein

Database

• OMIM: https://mirror.omim.org/entry/602701
• UniProt: http://www.uniprot.org/uniprot/Q14BN4.html