FXYD domain-containing ion transport regulator 5; dysadherin (FXYD5, DYSAD, IWU1, HSPC113, UNQ2561/PRO6241)

Function

• involved in down-regulation of E-cadherin, resulting in diminished cell adhesion

Structure

glycoprotein

Compartment

membrane

Alternative splicing

named isoforms=2

Pathology

promotes metastasis

More general terms

• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/606669
• UniProt: http://www.uniprot.org/uniprot/Q96DB9.html