CUB & SUSHI domain-containing protein 2; CUB & SUSHI multiple domains protein 2 (CSMD2, KIAA1884)

Structure

• belongs to the CSMD family
• contains 14 CUB domains
• contains 26 Sushi domains

Compartment

• cell membrane; single-pass membrane protein

Alternative splicing

named isoforms=3

Expression

• weakly expressed in most tissues, except in brain
• expressed at intermediate level in brain, including cerebellum, substantia nigra, hippocampus & fetal brain

Pathology

• overexpressed in some head & neck cancer cell lines

More general terms

• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=114784
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:114784
• OMIM: https://mirror.omim.org/entry/608398
• UniProt: http://www.uniprot.org/uniprot/Q7Z408.html