SL cytokine; Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L (FLT3LG)

Function

• stimulates the proliferation of early hematopoietic cells
• synergizes well with a number of other colony stimulating factors & interleukins
• homodimer (isoform 2)

Compartment

• isoform 1: cell membrane; single-pass type 1 membrane protein
• isoform 2: secreted

Alternative splicing

named isoforms=2

More general terms

• oligomerizing protein
• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2323
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2323
• OMIM: https://mirror.omim.org/entry/600007
• UniProt: http://www.uniprot.org/uniprot/P49771.html