protein ripply3; Down syndrome critical region protein 6 (DSCR6, RIPPLY3)

Structure

• the ripply homology domain is required for transcriptional repression (putative)
• the WRPW motif is required for binding to tle/groucho proteins (putative)
• belongs to the ripply family

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

Expression

• expressed at a low level in fetal kidney & fetal brain

More general terms

• Down syndrome critical region protein
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=53820
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:53820
• OMIM: https://mirror.omim.org/entry/609892
• UniProt: http://www.uniprot.org/uniprot/P57055.html