ninjurin-2; nerve injury-induced protein 2 (NINJ2)

Function

• homophilic cell adhesion molecule that promotes axonal growth
• may play a role in nerve regeneration & in the formation & function of other tissues

Structure

belongs to the ninjurin family

Compartment

membrane

Expression

• widely expressed
• in adult, expression in the bone marrow & peripheral blood lymphocytes > lung, lymph node, thyroid, uterus, thymus, spleen, prostate & skeletal muscle > liver, placenta, brain, heart & kidney
• in embryo, expression in the thymus, heart & liver > spleen, lung, brain & kidney
• induced by nerve injury; in Schwann cells

More general terms

• phosphoprotein
• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4815
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4815
• OMIM: https://mirror.omim.org/entry/607297
• UniProt: http://www.uniprot.org/uniprot/Q9NZG7.html