transport protein sec61-alpha (SEC61A)

Function

• role in the insertion of secretory & membrane polypeptides into the ER
• assembly of membrane & secretory proteins
• tightly associated with membrane-bound ribosomes, either directly or through adapter proteins
• component of protein transport protein SEC61

Structure

belongs to the secY/SEC61-alpha family

Compartment

endoplasmic reticulum

Alternative splicing

named isoforms=2 or 3

More general terms

• transmembrane 10 protein
• protein subunit

Component of

• protein transport protein SEC61

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2992
• OMIM: https://mirror.omim.org/entry/609213
• UniProt: http://www.uniprot.org/uniprot/P61619.html
• UniProt: http://www.uniprot.org/uniprot/Q9H9S3.html