serine/threonine protein kinase ICK; intestinal cell kinase; hICK; MAK-related kinase; MRK; laryngeal cancer kinase 2,; LCK2 (ICK, KIAA0936)
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Function
- may play a role in cardiac development
- phosphorylation at T14 or Y15 inactivates
- phosphorylation at T157 & Y159 activates
Compartment
Expression
- expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine & colon
Pathology
- expressed in many cancer cell lines