hedgehog interacting protein (HHIP, UNQ5825/PRO1964)

Function

• modulates hedgehog signaling in brain & lung
• interacts with all 3 hedgehog family members: SHH, IHH, DHH

Compartment

cell membrane; peripheral membrane, secreted

Alternative splicing

named isoforms=2

Expression

• widely expressed in fetal & adult tissues
• highest expression in adult heart, liver, pancreas, fetal kidney

More general terms

• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/606178
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64399
• UniProt: http://www.uniprot.org/uniprot/Q96QV1.html