adenylyl cyclase-associated protein 1; CAP-1 (CAP1, CAP)

Function

• directly regulates filament dynamics
• implicated in a number of complex developmental & morphological processes, including mRNA localization & the establishment of cell polarity
• binds actin monomers

Structure

• homodimer
• belongs to the CAP family
• contains 1 C-CAP/cofactor C-like domain

Compartment

cell membrane; peripheral membrane protein

Alternative splicing

named isoforms=2

More general terms

• membrane protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q01518.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10487
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10487