transmembrane serine protease 13 (mosaic serine protease, membrane-type mosaic serine protease, TMPRSS13, MSP, TMPRSS11)

Structure

• belongs to the peptidase S1 family
• contains 1 LDL-receptor class A domain
• contains 1 peptidase S1 domain
• contains 1 SRCR domain

Compartment

membrane

Alternative splicing

named isoforms=4

Expression

• isoform 1 & 3 are predominantly expressed in lung, placenta, pancreas, & prostate
• isoform 3 is weakly expressed in testis & peripheral blood lymphocytes

Polymorphism

• repeat A-S-P-A-[GLQR] is polymorphic, varies from 12-14 repeats

More general terms

• transmembrane serine protease
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BYE2.html