transmembrane serine protease 6 (matriptase-2, TMPRSS6)

Function

• specialized role in matrix remodeling processes in liver (putative)

Structure

• belongs to the peptidase S1 family
• contains 2 CUB domains
• contains 3 LDL-receptor class A domains
• contains 1 peptidase S1 domain

Compartment

membrane

Alternative splicing

named isoforms=3

Expression

liver specific

More general terms

• transmembrane serine protease
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IU80.html