lipase member I; membrane-associated phosphatidic acid-selective phospholipase A1-beta; mPA-PLA1 beta; LPD lipase (LIPI, LPDL, PRED5)

Function

• hydrolyzes phosphatidic acid to lysophosphatidic acid
• interacts with heparin

Inhibition:

• inhibited by sodium vanadate

Compartment

secreted, associate with lipid draft

Alternative splicing

named isoforms=2

Expression

• expressed in testis
• expressed exclusively at connecting piece of the sperm

Pathology

• defects in LIPI may be a cause of susceptibility to familial hypertrigliceridemia

More general terms

• lipase
• glycoprotein
• secreted protein

Database

• OMIM: https://mirror.omim.org/entry/145750
• UniProt: http://www.uniprot.org/uniprot/Q6XZB0.html