ATP-binding cassette sub-family A member 9 (ABCA9)

Function

• role in monocyte differentiation & lipid homeostasis (putative)

Structure

• belongs to the ABC transporter family, ABCA subfamily
• contains 2 ABC transporter domains

Compartment

membrane

Alternative splicing

named isoforms=5

Expression

• widely expressed with higher expression in heart
• expressed in fetal tissues with higher expression in fetal heart & kidney
• up-regulated during monocyte differentiation into macrophages
• down-regulated by cholesterol loading of macrophages

More general terms

• transmembrane 14 protein
• ATP-binding cassette sub-family A (ABC transporter-A, ABCA)
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IUA7.html