polycystic kidney disease & receptor for egg jelly-related protein (PKD & REJ homolog, PKDREJ)

Function

• role in fertilization
• may generate a Ca+2 transporting channel directly involved in initiating the acrosome reaction of the sperm
• may form homomultimers or heteromultimers in combination with unidentified subunits

Structure

• belongs to the polycystin family
• contains 1 PLAT domain
• contains 1 REJ domain

Compartment

membrane

Expression

• exclusively expressed in testis

More general terms

• testis-specific protein
• transmembrane 11e protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/604670
• UniProt: http://www.uniprot.org/uniprot/Q9NTG1.html