lysyl oxidase homolog 3 (lysyl oxidase-like protein 3, LOXL3, LOXL)

Function

Cofactor: Cu+2

Structure

• contains 1 lysine tyrosylquinone
• contains 4 SRCR domains
• lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine

Compartment

secreted

Expression

• widely expressed
• highest levels in placenta, heart, ovary, testis, small intestine, spleen

More general terms

• oxidoreductase
• metalloprotein
• secreted protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/607163
• UniProt: http://www.uniprot.org/uniprot/P58215.html