platelet-derived growth factor receptor-like protein; PDGFR-like protein; PDGF receptor beta-like tumor suppressor (PDGFRL, PRLTS)

Function

• forms a complex composed of PDGFRL, TNK2 & GRB2

Structure

• contains 2 Ig-like C2-type domains

Compartment

secreted

Expression

expressed in colon, lung, liver

Pathology

• defects in PDGFRL are associated with colorectal cancer

More general terms

• glycoprotein
• secreted protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5157
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5157
• OMIM: https://mirror.omim.org/entry/114500
• OMIM: https://mirror.omim.org/entry/604584
• UniProt: http://www.uniprot.org/uniprot/Q15198.html