solute carrier family 8 member 2; Na+/Ca+2 exchanger 2; Na+/Ca+2-exchange protein 2 (SLC8A2, KIAA1087, NCX2)

Function

• rapidly transports Ca+2 during excitation-contraction coupling
• Ca+2 is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (putative)

Structure

• belongs to the Na+/K+/Ca+2 exchanger family, SLC8 subfamily
• contains 2 calx-beta domains

Compartment

membrane

More general terms

• transmembrane 11e protein
• glycoprotein
• Ca+2 binding protein
• solute carrier family 8 (SLC8, SLC8A, Na+/Ca+2 exchanger)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6543
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6543
• OMIM: https://mirror.omim.org/entry/601901
• UniProt: http://www.uniprot.org/uniprot/Q9UPR5.html